Hydroxide → 2-Amino-1,3-thiazole-4-carboxylic acid, N-BOC protected

HRID 822063Notes

Reaction equation

HRID 822063 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][c:9]1[s:10][cH:11][c:12]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[n:13]1.[CH2:22]1[O:23][CH2:24][CH2:25][O:26][CH2:27]1.[Li+:21].[OH-:20].[OH2:19].[OH2:28]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][c:9]1[s:10][cH:11][c:12]([C:14](=[O:15])[OH:16])[n:13]1

Participants

6

Reactant 5

HCID 961HydroxideHCID 962Water2×HCID 28486Lithium ionHCID 312751,4-DioxaneHCID 22280595Ethyl 2-((tert-butoxycarbonyl)amino)-1,3-thiazole-4-carboxylate

Product 1

HCID 15020512-Amino-1,3-thiazole-4-carboxylic acid, N-BOC protected

Sources & evidence

ORD record
ord-eed70f0948bf4d79bec18fc618853331
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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