Tetrahydrofuran → 5-[4-(5-Fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl-2-(trifluoromethyl)pentylidenamino]quinoline-2-carboxylic acid diethylamide
Reaction equation
[CH2:1]([CH3:2])[N:3]([C:4](=[O:5])[c:6]1[n:7][c:8]2[cH:9][cH:10][cH:11][c:12]([NH2:16])[c:13]2[cH:14][cH:15]1)[CH2:17][CH3:18].[F:19][c:20]1[cH:21][cH:22][c:23]([O:38][CH3:39])[c:24]([C:26]([CH2:27][C:28]([CH:29]=[O:30])([C:31]([F:32])([F:33])[F:34])[OH:35])([CH3:36])[CH3:37])[cH:25]1.[O:40]1[CH2:41][CH2:42][CH2:43][CH2:44]1>>[CH2:1]([CH3:2])[N:3]([C:4](=[O:5])[c:6]1[n:7][c:8]2[cH:9][cH:10][cH:11][c:12]([N:16]=[CH:29][C:28]([CH2:27][C:26]([c:24]3[c:23]([O:38][CH3:39])[cH:22][cH:21][c:20]([F:19])[cH:25]3)([CH3:36])[CH3:37])([C:31]([F:32])([F:33])[F:34])[OH:35])[c:13]2[cH:14][cH:15]1)[CH2:17][CH3:18]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-ea3faac48dc8484eb70eee09dcfc5552
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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