4-Isopropylaniline → 8-Hydroxy-2-(4-isopropylphenyl)-2-aza-spiro[4.5]decan-1-one
Reaction equation
[CH2:1]([O:2][C:4](=[O:5])[C:6]1([CH2:13][CH2:14][O:3][CH3:15])[CH2:7][CH2:8][CH:9]([OH:12])[CH2:10][CH2:11]1)[CH3:16].[CH:17]([CH3:18])([CH3:19])[c:20]1[cH:21][cH:22][c:23]([NH2:24])[cH:25][cH:26]1>>[C:4]1(=[O:5])[C:6]2([CH2:7][CH2:8][CH:9]([OH:12])[CH2:10][CH2:11]2)[CH2:13][CH2:14][N:24]1[c:23]1[cH:22][cH:21][c:20]([CH:17]([CH3:18])[CH3:19])[cH:26][cH:25]1Participants
3
Sources & evidence
- ORD record
- ord-4a2002613f144f0092d8da8892300810
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…