Sodium ion → (4-Fluorooxan-4-yl)methanol

HRID 822736Notes

Reaction equation

HRID 822736 reaction equation
[BH4-:12].[CH3:14][CH:15]([OH:16])[CH3:17].[F:1][C:2]1([CH:8]([C:9]#[N:10])[OH:11])[CH2:3][CH2:4][O:5][CH2:6][CH2:7]1.[Na+:13].[OH2:18]>>[F:1][C:2]1([CH2:8][OH:11])[CH2:3][CH2:4][O:5][CH2:6][CH2:7]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 962WaterHCID 3776IsopropanolHCID 28123BorohydrideHCID 866153632-(4-fluorotetrahydro-2H-pyran-4-yl)-2-hydroxyacetonitrile

Product 1

HCID 56971676(4-Fluorooxan-4-yl)methanol

Sources & evidence

ORD record
ord-a01abfb6bf4642d6b41420ad7d6a7026
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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