Trifluoroacetic acid → N-[2-[6-[[2-(Acetylamino)-4-benzothiazolyl]oxy]-4-pyrimidinyl]-5-(trifluoromethyl)phenyl]-5,5-dimethyl-2-pyrrolidinecarboxamide
Reaction equation
[C:1]([CH3:2])(=[O:3])[NH:4][c:5]1[s:6][c:7]2[c:8]([n:9]1)[c:10]([O:14][c:15]1[cH:16][c:17](-[c:21]3[c:22]([NH:31][C:32](=[O:33])[CH:34]4[CH2:35][CH2:36][C:37]([CH3:46])([CH3:47])[N:38]4[C:39]([O:40][C:41]([CH3:42])([CH3:43])[CH3:44])=[O:45])[cH:23][c:24]([C:27]([F:28])([F:29])[F:30])[cH:25][cH:26]3)[n:18][cH:19][n:20]1)[cH:11][cH:12][cH:13]2.[F:48][C:49]([F:50])([F:51])[C:52]([OH:53])=[O:54]>>[C:1]([CH3:2])(=[O:3])[NH:4][c:5]1[s:6][c:7]2[c:8]([n:9]1)[c:10]([O:14][c:15]1[cH:16][c:17](-[c:21]3[c:22]([NH:31][C:32](=[O:33])[CH:34]4[CH2:35][CH2:36][C:37]([CH3:46])([CH3:47])[NH:38]4)[cH:23][c:24]([C:27]([F:28])([F:29])[F:30])[cH:25][cH:26]3)[n:18][cH:19][n:20]1)[cH:11][cH:12][cH:13]2Participants
3
Sources & evidence
- ORD record
- ord-580da8acc13144999e78f743bad0dbf1
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…