Potassium Cation → N-(4-(5-chlorobenzo[d]oxazol-2-yl)phenyl)-2-(3-fluorophenoxy)acetamide

HRID 822874Notes

Reaction equation

HRID 822874 reaction equation
[Br:15][CH2:16][C:17](=[O:18])[NH:19][c:20]1[cH:21][cH:22][c:23](-[c:26]2[o:27][c:28]3[c:29]([n:30]2)[cH:31][c:32]([Cl:35])[cH:33][cH:34]3)[cH:24][cH:25]1.[C:9](=[O:10])([O-:11])[O-:12].[F:1][c:2]1[cH:3][c:4]([OH:8])[cH:5][cH:6][cH:7]1.[K+:13].[K+:14].[O:36]=[CH:37][N:38]([CH3:39])[CH3:40].[OH2:41]>>[F:1][c:2]1[cH:3][c:4]([O:8][CH2:16][C:17](=[O:18])[NH:19][c:20]2[cH:21][cH:22][c:23](-[c:26]3[o:27][c:28]4[c:29]([n:30]3)[cH:31][c:32]([Cl:35])[cH:33][cH:34]4)[cH:24][cH:25]2)[cH:5][cH:6][cH:7]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 962WaterHCID 6228DimethylformamideHCID 97433-FluorophenolHCID 19660Carbonate IonHCID 579172332-bromo-N-[4-(5-chloro-1,3-benzoxazol-2-yl)phenyl]acetamide

Product 1

HCID 16126838N-(4-(5-chlorobenzo[d]oxazol-2-yl)phenyl)-2-(3-fluorophenoxy)acetamide

Sources & evidence

ORD record
ord-4ff349cd81434cac923a8bb8db1a9730
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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