Bromide ion → 1-Tert-butyloxycarbonyl-1,2,3,4-tetrahydro4-hydroxy-4-methylquinoline

HRID 822971Notes

Reaction equation

HRID 822971 reaction equation
[Br-:19].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11](=[O:18])[c:12]2[cH:13][cH:14][cH:15][cH:16][c:17]21.[CH2:22]1[O:23][CH2:24][CH2:25][CH2:26]1.[CH3:20][Mg+:21]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([OH:18])([CH3:20])[c:12]2[cH:13][cH:14][cH:15][cH:16][c:17]21

Participants

5

Reactant 4

HCID 259Bromide ionHCID 8028TetrahydrofuranHCID 23433504tert-Butyl 4-oxo-3,4-dihydroquinoline-1(2H)-carboxylateHCID 178477777HCID 178477777, compound

Product 1

HCID 234334501-Tert-butyloxycarbonyl-1,2,3,4-tetrahydro4-hydroxy-4-methylquinoline

Sources & evidence

ORD record
ord-deb6df4b8fda4e728251a937ef3f1049
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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