Toluene → Ethyl 2-(diethylamino)-4-trifluoromethyl-5-oxazolecarboxylate

HRID 823152Notes

Reaction equation

HRID 823152 reaction equation
[CH2:16]([CH3:17])[NH:18][CH2:19][CH3:20].[CH3:21][c:22]1[cH:23][cH:24][cH:25][cH:26][cH:27]1.[Cl:1][c:2]1[o:3][c:4]([C:11](=[O:12])[O:13][CH2:14][CH3:15])[c:5]([C:7]([F:8])([F:9])[F:10])[n:6]1>>[c:2]1([N:18]([CH2:16][CH3:17])[CH2:19][CH3:20])[o:3][c:4]([C:11](=[O:12])[O:13][CH2:14][CH3:15])[c:5]([C:7]([F:8])([F:9])[F:10])[n:6]1

Participants

4

Reactant 3

HCID 1140TolueneHCID 8021DiethylamineHCID 12785855Ethyl 2-chloro-4-(trifluoromethyl)oxazole-5-carboxylate

Product 1

HCID 20064751Ethyl 2-(diethylamino)-4-trifluoromethyl-5-oxazolecarboxylate

Sources & evidence

ORD record
ord-356960aa59234afab683c9fc1db6f590
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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