Phosphorus oxychloride → 2-(3-((2-Amino-4-chloro-6-methylpyrimidin-5-yl)methyl)-4-methoxyphenyl)acetonitrile

HRID 823237Notes

Reaction equation

HRID 823237 reaction equation
[NH2:1][c:2]1[n:3][c:4]([CH3:21])[c:5]([CH2:9][c:10]2[cH:11][c:12]([CH2:18][C:19]#[N:20])[cH:13][cH:14][c:15]2[O:16][CH3:17])[c:6]([OH:8])[n:7]1.[P:22]([Cl:23])([Cl:24])([Cl:25])=[O:26]>>[NH2:1][c:2]1[n:3][c:4]([CH3:21])[c:5]([CH2:9][c:10]2[cH:11][c:12]([CH2:18][C:19]#[N:20])[cH:13][cH:14][c:15]2[O:16][CH3:17])[c:6]([Cl:24])[n:7]1

Participants

3

Reactant 2

HCID 24813Phosphorus oxychlorideHCID 178490297HCID 178490297, compound

Product 1

HCID 866334152-(3-((2-Amino-4-chloro-6-methylpyrimidin-5-yl)methyl)-4-methoxyphenyl)acetonitrile

Sources & evidence

ORD record
ord-4f1fdc71bee84db68983182d2ff61a77
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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