Tetrahydrofuran → Tert-butyl 3-(3,5-difluoro-2-phenylmethoxybenzoyl)piperidine-1-carboxylate

HRID 823248Notes

Reaction equation

[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([Br:17])[cH:11][c:12]([F:16])[cH:13][c:14]1[F:15].[CH2:48]1[O:49][CH2:50][CH2:51][CH2:52]1.[CH3:18][CH2:19][CH2:20][CH2:21][Li:22].[CH3:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28].[CH3:29][O:30][N:31]([C:32](=[O:33])[CH:34]1[CH2:35][N:36]([C:40](=[O:41])[O:42][C:43]([CH3:44])([CH3:45])[CH3:46])[CH2:37][CH2:38][CH2:39]1)[CH3:47]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([C:32](=[O:33])[CH:34]2[CH2:35][N:36]([C:40](=[O:41])[O:42][C:43]([CH3:44])([CH3:45])[CH3:46])[CH2:37][CH2:38][CH2:39]2)[cH:11][c:12]([F:16])[cH:13][c:14]1[F:15]