Hydrochloric Acid → N-[1-(4-acetamidocyclohexanecarbonyl)-3-(4-methylphenyl)piperidin-4-yl]-N-methyl-3,5-bis(trifluoromethyl)benzamide
Reaction equation
[C:33]([CH3:34])(=[O:35])[NH:36][CH:37]1[CH2:38][CH2:39][CH:40]([C:43](=[O:44])[OH:45])[CH2:41][CH2:42]1.[CH3:2][N:3]([C:4]([c:5]1[cH:6][c:7]([C:15]([F:16])([F:17])[F:18])[cH:8][c:9]([C:11]([F:12])([F:13])[F:14])[cH:10]1)=[O:19])[CH:20]1[CH:21]([c:26]2[cH:27][cH:28][c:29]([CH3:32])[cH:30][cH:31]2)[CH2:22][NH:23][CH2:24][CH2:25]1.[ClH:1]>>[CH3:2][N:3]([C:4]([c:5]1[cH:6][c:7]([C:15]([F:16])([F:17])[F:18])[cH:8][c:9]([C:11]([F:12])([F:13])[F:14])[cH:10]1)=[O:19])[CH:20]1[CH:21]([c:26]2[cH:27][cH:28][c:29]([CH3:32])[cH:30][cH:31]2)[CH2:22][N:23]([C:43]([CH:40]2[CH2:39][CH2:38][CH:37]([NH:36][C:33]([CH3:34])=[O:35])[CH2:42][CH2:41]2)=[O:44])[CH2:24][CH2:25]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-aee67ea55b674f5ba216bbbdbc107d58
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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