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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 824142Generated: October 30, 2026

Acetic Acid → 5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-[(3-methylpiperazin-1-yl)methyl]-3,4-dihydroquinazolin-2(1H)-one

https://huagongshe.com/reaction/824142

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantHydrogen BromideHCID 260—
ReactantDichloromethaneHCID 6344—
ReactantBenzyl 4-{[5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-2-oxo-1,2,3,4-tetrahydroquinazolin-7-yl]methyl}-2-methylpiperazine-1-carboxylateHCID 22647930—
Product5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-[(3-methylpiperazin-1-yl)methyl]-3,4-dihydroquinazolin-2(1H)-oneHCID 10186112—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-927a70bc4f53452da525e423972e6032
Source noteTest data from https://doi.org/10.1039/C8SC04228D