Pyrrolidine → 6-[2-(4-Cyclobutylpiperazin-1-Yl)-2-Oxoethyl]-2-Pyrrolidin-1-Yl-5,6,7,8-Tetrahydro-1,6-Naphthyridine
Reaction equation
[CH2:25]1[CH2:26][CH2:27][NH:28][CH2:29]1.[Cl:1][c:2]1[n:3][c:4]2[c:9]([cH:10][cH:11]1)[CH2:8][N:7]([CH2:12][C:13](=[O:14])[N:15]1[CH2:16][CH2:17][N:18]([CH:21]3[CH2:22][CH2:23][CH2:24]3)[CH2:19][CH2:20]1)[CH2:6][CH2:5]2>>[c:2]1([N:28]2[CH2:27][CH2:26][CH2:25][CH2:29]2)[n:3][c:4]2[c:9]([cH:10][cH:11]1)[CH2:8][N:7]([CH2:12][C:13](=[O:14])[N:15]1[CH2:16][CH2:17][N:18]([CH:21]3[CH2:22][CH2:23][CH2:24]3)[CH2:19][CH2:20]1)[CH2:6][CH2:5]2Participants
3
Sources & evidence
- ORD record
- ord-5b73952db94a4bbba8e416c6cdd49dda
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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