Dichloromethane → HCID 178516737, compound

HRID 824424Notes

Reaction equation

[Cl:46][CH2:47][Cl:48].[F:1][C:2]([c:3]1[c:4]([N:9]2[CH2:10][C:11](=[O:36])[N:12]([c:15]3[n:16][c:17]4[c:18]([n:19]3[CH2:20][O:21][CH2:22][CH2:23][Si:24]([CH3:25])([CH3:26])[CH3:27])[cH:28][cH:29][c:30]([C:32]([F:33])([F:34])[F:35])[cH:31]4)[CH2:13][CH2:14]2)[n:5][cH:6][cH:7][cH:8]1)([F:37])[F:38].[F:39][C:40]([F:41])([F:42])[C:43]([OH:44])=[O:45]>>[F:1][C:2]([c:3]1[c:4]([N:9]2[CH2:10][C:11](=[O:36])[N:12]([c:15]3[n:16][c:17]4[c:18]([nH:19]3)[cH:28][cH:29][c:30]([C:32]([F:33])([F:34])[F:35])[cH:31]4)[CH2:13][CH2:14]2)[n:5][cH:6][cH:7][cH:8]1)([F:37])[F:38]

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 865938294-(3-Trifluoromethyl-pyridin-2-yl)-1-[5-trifluoromethyl-1-(2-trimethylsilanyl-ethoxymethyl)-1H-benzoimidazol-2-yl]-piperazin-2-one

Product 1

HCID 178516737HCID 178516737, compound

Sources & evidence

ORD record: ord-86e81d7580a94fe184d25c38116d7e63
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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