Methanol → 5-Chloro-2-methylamino-4-(4-methyl-piperazin-1-yl)-aniline

HRID 824451Notes

Reaction equation

HRID 824451 reaction equation
[CH2:20]1[O:21][CH2:22][CH2:23][CH2:24]1.[CH3:25][OH:26].[Cl:1][c:2]1[cH:3][c:4]([N+:17]([O-:18])=[O:19])[c:5]([NH:6][CH3:7])[cH:8][c:9]1[N:10]1[CH2:11][CH2:12][N:13]([CH3:16])[CH2:14][CH2:15]1>>[Cl:1][c:2]1[cH:3][c:4]([NH2:17])[c:5]([NH:6][CH3:7])[cH:8][c:9]1[N:10]1[CH2:11][CH2:12][N:13]([CH3:16])[CH2:14][CH2:15]1

Participants

4

Reactant 3

HCID 887MethanolHCID 8028TetrahydrofuranHCID 441206494-Chloro-5-(4-methyl-piperazin-1-yl)-2-nitro-N-methyl-aniline

Product 1

HCID 679579235-Chloro-2-methylamino-4-(4-methyl-piperazin-1-yl)-aniline

Sources & evidence

ORD record
ord-eb1db354eaba4d16b698b3c730905d9b
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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