Dimethyl Sulfoxide → 4-(6-Nitropyridin-3-yl)morpholine

HRID 825386Notes

Reaction equation

HRID 825386 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([N+:8](=[O:9])[O-:10])[n:6][cH:7]1.[CH2:17]1[CH2:18][O:19][CH2:20][CH2:21][NH:22]1.[CH2:24]([N+:25]([CH2:26][CH2:27][CH2:28][CH3:29])([CH2:30][CH2:31][CH2:32][CH3:33])[CH2:34][CH2:35][CH2:36][CH3:37])[CH2:38][CH2:39][CH3:40].[CH3:41][S:42]([CH3:43])=[O:44].[CH3:45][CH2:46][O:47][C:48](=[O:49])[CH3:50].[I-:23].[K+:11].[K+:12].[O-:13][C:14]([O-:15])=[O:16]>>[c:2]1([N:22]2[CH2:17][CH2:18][O:19][CH2:20][CH2:21]2)[cH:3][cH:4][c:5]([N+:8](=[O:9])[O-:10])[n:6][cH:7]1

Participants

9

Reactant 8

HCID 679Dimethyl SulfoxideHCID 813Potassium Cation2×HCID 8083MorpholineHCID 8857Ethyl AcetateHCID 16028TetrabutylammoniumHCID 19660Carbonate IonHCID 30165Iodide IonHCID 8176205-Bromo-2-nitropyridine

Product 1

HCID 29279734-(6-Nitropyridin-3-yl)morpholine

Sources & evidence

ORD record
ord-2e01bdbd51a04de089f8efaaa8f536ea
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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