Hydroxide → 3-[1-[(2-Methylpropan-2-yl)oxycarbonyl]azetidin-3-yl]prop-2-enoic acid

HRID 825389Notes

Reaction equation

HRID 825389 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([CH:12]=[CH:13][C:14](=[O:15])[O:16][CH2:17][CH3:18])[CH2:11]1.[CH2:22]1[O:23][CH2:24][CH2:25][O:26][CH2:27]1.[Li+:19].[OH-:20].[OH2:21]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([CH:12]=[CH:13][C:14](=[O:15])[OH:16])[CH2:11]1

Participants

6

Reactant 5

HCID 961HydroxideHCID 962WaterHCID 28486Lithium ionHCID 312751,4-DioxaneHCID 54064623Tert-butyl 3-(3-ethoxy-3-oxo-prop-1-enyl)azetidine-1-carboxylate

Product 1

HCID 540086093-[1-[(2-Methylpropan-2-yl)oxycarbonyl]azetidin-3-yl]prop-2-enoic acid

Sources & evidence

ORD record
ord-b80219706bc34a0ea92d65dbf2d48e54
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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