Ammonia → 5-Thiazolecarboxamide, 2-(2-methoxyphenyl)-4-methyl-

HRID 825439Notes

Reaction equation

HRID 825439 reaction equation
[CH3:21][O:22][c:23]1[cH:24][cH:25][cH:26][cH:28][c:29]1[C:30]([NH2:27])=[O:31].[CH3:2][O:3][c:4]1[c:5](-[c:10]2[s:11][c:12]([C:16]([O:18][CH2:17][CH3:19])=[O:20])[c:13]([CH3:15])[n:14]2)[cH:6][cH:7][cH:8][cH:9]1.[CH3:56][CH2:57][OH:58].[Cl:32][CH:33]([C:34]([CH3:35])=[O:36])[C:37]([O:38][CH2:39][CH3:40])=[O:41].[NH3:1].[P:42]12(=[S:55])[S:43][P:44]3(=[S:54])[S:45][P:46](=[S:52])([S:47][P:48](=[S:51])([S:49]3)[S:50]1)[S:53]2>>[CH3:2][O:3][c:4]1[c:5](-[c:10]2[s:11][c:12]([C:16](=[O:18])[NH2:27])[c:13]([CH3:15])[n:14]2)[cH:6][cH:7][cH:8][cH:9]1

Participants

7

Reactant 6

HCID 222AmmoniaHCID 702EthanolHCID 11858Ethyl 2-chloroacetoacetateHCID 14817Phosphorus sulfide (P2S5)HCID 755402-MethoxybenzamideHCID 13576837Ethyl 4-Methyl-2-(2-methoxyphenyl)thiazole-5-carboxylate

Product 1

HCID 30680725-Thiazolecarboxamide, 2-(2-methoxyphenyl)-4-methyl-

Sources & evidence

ORD record
ord-036df9ac83f8432887159a40da30101d
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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