Acetate → N-(1-ethylpyrazol-5-yl)-4-carboxyanthranilic acid

HRID 825477Notes

Reaction equation

HRID 825477 reaction equation
[Br:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[cH:7][cH:8][c:9]([C:11](=[O:12])[OH:13])[cH:10]1.[C:33]([O-:34])(=[O:35])[CH3:36].[C:38]([O-:39])(=[O:40])[CH3:41].[CH3:42][C:43](=[O:44])[OH:45].[Cu+2:37].[K+:27].[K+:28].[NH2:19][c:20]1[cH:21][cH:22][n:23][n:24]1[CH2:25][CH3:26].[O-:29][C:30]([O-:31])=[O:32].[O:14]=[CH:15][N:16]([CH3:17])[CH3:18].[OH2:46]>>[c:2]1([NH:19][c:20]2[cH:21][cH:22][n:23][n:24]2[CH2:25][CH3:26])[c:3]([C:4](=[O:5])[OH:6])[cH:7][cH:8][c:9]([C:11](=[O:12])[OH:13])[cH:10]1

Participants

10

Reactant 9

HCID 175Acetate2×HCID 176Acetic AcidHCID 813Potassium Cation2×HCID 962WaterHCID 6228DimethylformamideHCID 19660Carbonate IonHCID 27099Cupric cationHCID 68513Bromoterephthalic acidHCID 3373101-Ethyl-1H-pyrazol-5-amine

Product 1

HCID 21217714N-(1-ethylpyrazol-5-yl)-4-carboxyanthranilic acid

Sources & evidence

ORD record
ord-a2611e0600ae46e4910a6e234508f8aa
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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