Potassium Cation → N-(6-(1H-indazol-5-yl)naphthalen-2-yl)thiophene-3-carboxamide

HRID 825633Notes

Reaction equation

HRID 825633 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[cH:5][n:6][nH:7][c:8]2[cH:9][cH:10]1.[C:44](=[O:45])([O-:46])[O-:47].[CH2:52]([Cl:53])[Cl:54].[CH2:55]1[O:56][CH2:57][CH2:58][O:59][CH2:60]1.[CH3:11][C:12]1([CH3:13])[C:14]([CH3:15])([CH3:16])[O:17][B:18]([c:19]2[cH:20][c:21]3[cH:22][cH:23][c:24]([NH:29][C:30](=[O:31])[c:32]4[cH:33][s:34][cH:35][cH:36]4)[cH:25][c:26]3[cH:27][cH:28]2)[O:37]1.[K+:38].[K+:39].[Na+:48].[Na+:49].[O-:40][C:41]([O-:42])=[O:43].[OH2:51].[Pd:50]>>[c:2]1(-[c:19]2[cH:20][c:21]3[cH:22][cH:23][c:24]([NH:29][C:30](=[O:31])[c:32]4[cH:33][s:34][cH:35][cH:36]4)[cH:25][c:26]3[cH:27][cH:28]2)[cH:3][c:4]2[cH:5][n:6][nH:7][c:8]2[cH:9][cH:10]1

Participants

10

Reactant 9

HCID 813Potassium Cation2×HCID 923Sodium ion2×HCID 962WaterHCID 6344DichloromethaneHCID 19660Carbonate Ion2×HCID 23938PalladiumHCID 312751,4-DioxaneHCID 7619295-bromo-1H-indazoleHCID 67386422N-(6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-2-yl)thiophene-3-carboxamide

Product 1

HCID 58828843N-(6-(1H-indazol-5-yl)naphthalen-2-yl)thiophene-3-carboxamide

Sources & evidence

ORD record
ord-f60c40b625344d1793f01bf2187a0a1a
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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