Water → 6-(4-Chloro-benzylamino)-2-fluoro-nicotinic acid methyl ester
Reaction equation
[CH3:1][O:2][C:3]([c:4]1[c:5]([F:11])[n:6][c:7]([F:10])[cH:8][cH:9]1)=[O:12].[CH3:23][N:24]([CH3:25])[CH:26]=[O:27].[Cl:13][c:14]1[cH:15][cH:16][c:17]([CH2:18][NH2:19])[cH:20][cH:21]1.[OH2:22]>>[CH3:1][O:2][C:3]([c:4]1[c:5]([F:11])[n:6][c:7]([NH:19][CH2:18][c:17]2[cH:16][cH:15][c:14]([Cl:13])[cH:21][cH:20]2)[cH:8][cH:9]1)=[O:12]Participants
5
Sources & evidence
- ORD record
- ord-4f3886e6fe774a0a80c228df7e2fc92b
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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