Methanol → 3-(Phenyl(4-(trifluoromethyl)phenyl)methyl)piperidine
Reaction equation
[CH3:26][CH2:27][CH2:28][CH2:29][CH3:30].[CH3:31][OH:32].[H:24][H:25].[c:1]1([C:7](=[C:8]2[CH2:9][NH:10][CH2:11][CH2:12][CH2:13]2)[c:14]2[cH:15][cH:16][c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][cH:19]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([CH:7]([CH:8]2[CH2:9][NH:10][CH2:11][CH2:12][CH2:13]2)[c:14]2[cH:15][cH:16][c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][cH:19]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1Participants
5
Sources & evidence
- ORD record
- ord-20ffee14f8d449a58f4e9d6af9a3f2b1
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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