Acetate → Methyl 2-[3-[2-methyl-4-[3-[3-methyl-4-[4,4,4-trifluoro-3-hydroxy-3-(trifluoromethyl)but-1-enyl]phenyl]pentan-3-yl]phenyl]phenyl]acetate
Reaction equation
[C:102]([O-:103])(=[O:104])[CH3:105].[C:97]([O-:98])(=[O:99])[CH3:100].[CH2:38]([CH3:39])[C:40]([CH2:41][CH3:42])([c:43]1[cH:44][c:45]([CH3:58])[c:46]([B:49]2[O:50][C:51]([CH3:52])([CH3:53])[C:54]([CH3:55])([CH3:56])[O:57]2)[cH:47][cH:48]1)[c:59]1[cH:60][c:61]([CH3:77])[c:62]([CH:65]=[CH:66][C:67]([C:68]([F:69])([F:70])[F:71])([OH:72])[C:73]([F:74])([F:75])[F:76])[cH:63][cH:64]1.[CH3:78][O:79][C:80]([CH2:81][c:82]1[cH:83][c:84]([Br:88])[cH:85][cH:86][cH:87]1)=[O:89].[CH3:90][c:91]1[cH:92][cH:93][cH:94][cH:95][cH:96]1.[CH:1]1([P:2]([CH:3]2[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][c:14]2-[c:15]2[c:16]([O:17][CH3:18])[cH:19][cH:20][cH:21][c:22]2[O:23][CH3:24])[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29]1.[K+:35].[K+:36].[K+:37].[OH2:106].[P:30]([O-:31])([O-:32])([O-:33])=[O:34].[Pd+2:101]>>[CH2:38]([CH3:39])[C:40]([CH2:41][CH3:42])([c:43]1[cH:44][c:45]([CH3:58])[c:46](-[c:84]2[cH:83][c:82]([CH2:81][C:80]([O:79][CH3:78])=[O:89])[cH:87][cH:86][cH:85]2)[cH:47][cH:48]1)[c:59]1[cH:60][c:61]([CH3:77])[c:62]([CH:65]=[CH:66][C:67]([C:68]([F:69])([F:70])[F:71])([OH:72])[C:73]([F:74])([F:75])[F:76])[cH:63][cH:64]1Participants
10
Reactant 9
HCID 175Acetate2×
HCID 813Potassium Cation3×
HCID 962Water
HCID 1061Phosphate
HCID 1140Toluene
HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)
HCID 112698722-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl
HCID 11746402Methyl 2-(3-bromophenyl)acetate
HCID 765996721,1,1-Trifluoro-4-[2-methyl-4-[3-[3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pentan-3-yl]phenyl]-2-(trifluoromethyl)but-3-en-2-olProduct 1
Sources & evidence
- ORD record
- ord-094b8527cf0d46fcaab3357fee519cd5
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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