Tetrahydrofuran → [8-(3-Chloro-4-fluoro-phenyl)-6-cyclopropyl-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-[1-(6-methyl-pyrimidin-4-yl)-piperidin-4-yl]-amine

HRID 825967Notes

Reaction equation

[CH2:1]([Sn:2]([Cl:3])([Cl:4])[CH2:5][CH2:6][CH2:7][CH3:8])[CH2:9][CH2:10][CH3:11].[CH2:54]1[O:55][CH2:56][CH2:57][CH2:58]1.[CH3:33][c:34]1[cH:35][c:36]([N:40]2[CH2:41][CH2:42][C:43](=[O:46])[CH2:44][CH2:45]2)[n:37][cH:38][n:39]1.[Cl:12][c:13]1[cH:14][c:15](-[c:20]2[c:21]3[n:22]([cH:23][c:24]([CH:26]4[CH2:27][CH2:28]4)[cH:25]2)[n:29][c:30]([NH2:32])[n:31]3)[cH:16][cH:17][c:18]1[F:19].[c:47]1([SiH3:48])[cH:49][cH:50][cH:51][cH:52][cH:53]1>>[Cl:12][c:13]1[cH:14][c:15](-[c:20]2[c:21]3[n:22]([cH:23][c:24]([CH:26]4[CH2:27][CH2:28]4)[cH:25]2)[n:29][c:30]([NH:32][CH:43]2[CH2:42][CH2:41][N:40]([c:36]4[cH:35][c:34]([CH3:33])[n:39][cH:38][n:37]4)[CH2:45][CH2:44]2)[n:31]3)[cH:16][cH:17][c:18]1[F:19]