Trifluoroacetic acid → (3-(4-((3-Ethyl-3-hydroxyazetidin-1-yl)methyl)-2-methylphenoxy)azetidin-1-yl)(5-phenyl-1,3,4-oxadiazol-2-yl)methanone

HRID 826019Notes

Reaction equation

HRID 826019 reaction equation
[CH2:35]([CH3:36])[C:37]1([OH:41])[CH2:38][NH:39][CH2:40]1.[CH3:1][c:2]1[cH:3][c:4]([CH:5]=[O:6])[cH:7][cH:8][c:9]1[O:10][CH:11]1[CH2:12][N:13]([C:15](=[O:16])[c:17]2[o:18][c:19](-[c:22]3[cH:23][cH:24][cH:25][cH:26][cH:27]3)[n:20][n:21]2)[CH2:14]1.[F:28][C:29]([F:30])([F:31])[C:32]([OH:33])=[O:34]>>[CH3:1][c:2]1[cH:3][c:4]([CH2:5][N:39]2[CH2:38][C:37]([CH2:35][CH3:36])([OH:41])[CH2:40]2)[cH:7][cH:8][c:9]1[O:10][CH:11]1[CH2:12][N:13]([C:15](=[O:16])[c:17]2[o:18][c:19](-[c:22]3[cH:23][cH:24][cH:25][cH:26][cH:27]3)[n:20][n:21]2)[CH2:14]1

Participants

4

Reactant 3

HCID 6422Trifluoroacetic acidHCID 198883793-Ethylazetidin-3-olHCID 580430913-Methyl-4-(1-(5-Phenyl-1,3,4-oxadiazole-2-carbonyl)azetidin-3-yloxy)benzaldehyde

Product 1

HCID 56598800(3-(4-((3-Ethyl-3-hydroxyazetidin-1-yl)methyl)-2-methylphenoxy)azetidin-1-yl)(5-phenyl-1,3,4-oxadiazol-2-yl)methanone

Sources & evidence

ORD record
ord-cfce7af5943c450581411a4b36171bb5
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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