Ethyl Acetate → Di-tert-butyl 2-(2-amino-4-methylphenyl)malonate

HRID 826183Notes

Reaction equation

HRID 826183 reaction equation
[CH3:1][c:2]1[cH:3][c:4]([N+:23]([O-:24])=[O:25])[c:5]([CH:8]([C:9](=[O:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[cH:6][cH:7]1.[CH3:26][CH2:27][O:28][C:29](=[O:30])[CH3:31]>>[CH3:1][c:2]1[cH:3][c:4]([NH2:23])[c:5]([CH:8]([C:9](=[O:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 8857Ethyl AcetateHCID 57856684Di-tert-butyl 2-(4-methyl-2-nitrophenyl)malonate

Product 1

HCID 57856669Di-tert-butyl 2-(2-amino-4-methylphenyl)malonate

Sources & evidence

ORD record
ord-b0778696d13449fc92750c3f34542256
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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