HRID826317

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID313

Hydrochloric Acid

ClH

HCID923

Sodium ion

Na+

HCID962

Water

H2O

HCID95834

Morpholine, 4-(3-chloropropyl)-

C7H14ClNO

HCID166653

Hydride

H-

HCID76750894

未命名化合物

HCID86653555

2-amino-7-(4-fluoro-biphenyl-2-yl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-(3-dimethylamino-propyl)-oxime

C26H30FN5O

PRODUCTS

产物

HCID76750901

2-Amino-7-biphenyl-2-yl-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-(3-morpholin-4-yl-propyl)-oxime

C28H33N5O2

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-df0716eea8ba4c35a9e21155f9bc336e
来源数据集: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Test data from https://doi.org/10.1039/C8SC04228D

反应SMILES

[CH3:40][N:41]([CH3:42])[CH2:43][CH2:44][CH2:45][O:46][N:47]=[C:48]1[CH2:49][CH:50]([c:51]2[cH:52][c:53]([F:54])[cH:55][cH:56][c:57]2-[c:58]2[cH:59][cH:60][cH:61][cH:62][cH:63]2)[CH2:64][c:65]2[n:66][c:67]([NH2:68])[n:69][c:70]([CH3:71])[c:72]21.[Cl:28][CH2:29][CH2:30][CH2:31][N:32]1[CH2:33][CH2:34][O:35][CH2:36][CH2:37]1.[ClH:27].[H-:38].[NH2:1][c:2]1[n:3][c:4]2[c:9]([c:10]([CH3:12])[n:11]1)[C:8](=[N:13][OH:14])[CH2:7][CH:6]([c:15]1[c:16](-[c:21]3[cH:22][cH:23][cH:24][cH:25][cH:26]3)[cH:17][cH:18][cH:19][cH:20]1)[CH2:5]2.[Na+:39].[OH2:73]>>[NH2:1][c:2]1[n:3][c:4]2[c:9]([c:10]([CH3:12])[n:11]1)[C:8](=[N:13][O:14][CH2:29][CH2:30][CH2:31][N:32]1[CH2:33][CH2:34][O:35][CH2:36][CH2:37]1)[CH2:7][CH:6]([c:15]1[c:16](-[c:21]3[cH:22][cH:23][cH:24][cH:25][cH:26]3)[cH:17][cH:18][cH:19][cH:20]1)[CH2:5]2