Toluene → 4-[6-(5-Methanesulfonyl-2,3-dihydro-indol-1-yl)-pyrimidin-4-yl-methylamino]-piperidine-1-carboxylic acid isopropyl ester

HRID 826449Notes

Reaction equation

[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[cH:6][c:7]2[c:11]([cH:12][cH:13]1)[N:10]([c:14]1[cH:15][c:16]([N:20]([CH3:21])[CH:22]3[CH2:23][CH2:24][NH:25][CH2:26][CH2:27]3)[n:17][cH:18][n:19]1)[CH2:9][CH2:8]2.[CH3:28][CH2:29][N:30]([CH2:31][CH3:32])[CH2:33][CH3:34].[CH3:45][c:46]1[cH:47][cH:48][cH:49][cH:50][cH:51]1.[Cl:35][C:36](=[O:37])[O:38][CH:39]([CH3:40])[CH3:41].[Cl:42][CH2:43][Cl:44]>>[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[cH:6][c:7]2[c:11]([cH:12][cH:13]1)[N:10]([c:14]1[cH:15][c:16]([N:20]([CH3:21])[CH:22]3[CH2:23][CH2:24][N:25]([C:36](=[O:37])[O:38][CH:39]([CH3:40])[CH3:41])[CH2:26][CH2:27]3)[n:17][cH:18][n:19]1)[CH2:9][CH2:8]2