Tetrahydrofuran → Tert-butyl 4-(((6-cyano-4-(4-(((cyclopropylamino)carbonyl) amino)-3-fluorophenoxy)-7-quinolyl)oxy)methyl)-1-piperidinecarboxylate
Reaction equation
[C:1](#[N:2])[c:3]1[cH:4][c:5]2[c:6]([O:28][c:29]3[cH:30][c:31]([F:45])[c:32]([NH:35][C:36]([O:38][c:37]4[cH:39][cH:40][cH:41][cH:42][cH:43]4)=[O:44])[cH:33][cH:34]3)[cH:7][cH:8][n:9][c:10]2[cH:11][c:12]1[O:13][CH2:14][CH:15]1[CH2:16][CH2:17][N:18]([C:21](=[O:22])[O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:19][CH2:20]1.[CH:46]1([NH2:49])[CH2:47][CH2:48]1.[O:50]1[CH2:51][CH2:52][CH2:53][CH2:54]1>>[C:1](#[N:2])[c:3]1[cH:4][c:5]2[c:6]([O:28][c:29]3[cH:30][c:31]([F:45])[c:32]([NH:35][C:36](=[O:38])[NH:49][CH:46]4[CH2:47][CH2:48]4)[cH:33][cH:34]3)[cH:7][cH:8][n:9][c:10]2[cH:11][c:12]1[O:13][CH2:14][CH:15]1[CH2:16][CH2:17][N:18]([C:21](=[O:22])[O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:19][CH2:20]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-c4fdda2b386246b5a4af623b1ae5868c
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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