Benzyl Alcohol → 2-Amino-4-benzyloxy-5-nitropyrimidine

HRID 826859Notes

Reaction equation

[NH2:1][c:2]1[n:3][cH:4][c:5]([N+:9](=[O:10])[O-:11])[c:6]([Cl:8])[n:7]1.[Na:12].[OH:13][CH2:14][c:15]1[cH:16][cH:17][cH:18][cH:19][cH:20]1>>[NH2:1][c:2]1[n:3][cH:4][c:5]([N+:9](=[O:10])[O-:11])[c:6]([O:13][CH2:14][c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[n:7]1

Participants

Reactant 3

HCID 244Benzyl Alcohol

HCID 3199954-chloro-5-nitropyrimidin-2-amine

HCID 5360545Sodium

Product 1

HCID 102639222-Amino-4-benzyloxy-5-nitropyrimidine

Sources & evidence

ORD record: ord-8f2e5330098a49009ac8c748165b7cf5
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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