HRID826951

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6344

Dichloromethane

CH2Cl2

HCID8083

Morpholine

C4H9NO

HCID15908

1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide

C8H17N3

HCID75771

1-Hydroxybenzotriazole

C6H5N3O

结构：CC(C)(C)OC(=O)C(C)(C)Sc1nc(CCOc2ccc(-c3ccc(F)cc3)cc2C(=O)O)cs1

HCID59759162

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)C(C)(C)Sc1nc(CCOc2ccc(-c3ccc(F)cc3)cc2C(=O)N2CCOCC2)cs1

HCID59759195

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-1300ae08ebb04851a21947e285aca2c7
来源数据集: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Test data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[CH2:36]1[CH2:37][O:38][CH2:39][CH2:40][NH:41]1.[CH3:42][N:43]([CH3:44])[CH2:45][CH2:46][CH2:47][N:48]=[C:49]=[N:50][CH2:51][CH3:52].[Cl:63][CH2:64][Cl:65].[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10]([C:33](=[O:34])[OH:35])[c:11]([O:14][CH2:15][CH2:16][c:17]3[n:18][c:19]([S:22][C:23]([C:24](=[O:25])[O:26][C:27]([CH3:28])([CH3:29])[CH3:30])([CH3:31])[CH3:32])[s:20][cH:21]3)[cH:12][cH:13]2)[cH:6][cH:7]1.[OH:53][n:54]1[c:55]2[cH:56][cH:57][cH:58][cH:59][c:60]2[n:61][n:62]1>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10]([C:33](=[O:35])[N:41]3[CH2:36][CH2:37][O:38][CH2:39][CH2:40]3)[c:11]([O:14][CH2:15][CH2:16][c:17]3[n:18][c:19]([S:22][C:23]([C:24](=[O:25])[O:26][C:27]([CH3:28])([CH3:29])[CH3:30])([CH3:31])[CH3:32])[s:20][cH:21]3)[cH:12][cH:13]2)[cH:6][cH:7]1