Acetate → 2-(2'-Bromobiphenyl-4-yl)benzoxazole

HRID 827000Notes

Reaction equation

HRID 827000 reaction equation
[Br:17][c:18]1[c:19]([B:24]([OH:25])[OH:26])[cH:20][cH:21][cH:22][cH:23]1.[C:49](=[O:50])([O-:51])[O-:52].[CH3:64][O:65][CH2:66][CH2:67][O:68][CH3:69].[I:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[o:9][c:10]3[c:11]([n:12]2)[cH:13][cH:14][cH:15][cH:16]3)[cH:6][cH:7]1.[K+:53].[K+:54].[O-:56][C:57]([CH3:58])=[O:59].[O-:60][C:61]([CH3:62])=[O:63].[Pd+2:55].[c:27]1([CH3:28])[cH:29][cH:30][cH:31][cH:32][c:33]1[P:34]([c:35]1[cH:36][cH:37][cH:38][cH:39][c:40]1[CH3:41])[c:42]1[cH:43][cH:44][cH:45][cH:46][c:47]1[CH3:48]>>[c:2]1(-[c:19]2[c:18]([Br:17])[cH:23][cH:22][cH:21][cH:20]2)[cH:3][cH:4][c:5](-[c:8]2[o:9][c:10]3[c:11]([n:12]2)[cH:13][cH:14][cH:15][cH:16]3)[cH:6][cH:7]1

Participants

9

Reactant 8

HCID 175Acetate2×HCID 813Potassium Cation2×HCID 80711,2-DimethoxyethaneHCID 19660Carbonate IonHCID 80271Tri-o-tolylphosphineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 2773294(2-Bromophenyl)boronic acidHCID 28294142-(4-Iodophenyl)benzoxazole

Product 1

HCID 592285352-(2'-Bromobiphenyl-4-yl)benzoxazole

Sources & evidence

ORD record
ord-95071e9cac714411b21c23f746090fbc
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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