Acetic Acid → N-[2-(2-amino-6-methoxy-benzoyl)-5-chloro-pyridin-3-yl]-4-chloro-3-trifluoromethyl-benzenesulfonamide

HRID 827097Notes

Reaction equation

HRID 827097 reaction equation
[C:45]([OH:46])(=[O:47])[CH3:48].[Cl:1][c:2]1[cH:3][c:4]([NH:25][S:26](=[O:27])(=[O:28])[c:29]2[cH:30][c:31]([C:36]([F:37])([F:38])[F:39])[c:32]([Cl:35])[cH:33][cH:34]2)[c:5]([C:8](=[O:9])[c:10]2[c:11]([NH:18][C:19](=[O:20])[C:21]([CH3:22])([CH3:23])[CH3:24])[cH:12][cH:13][cH:14][c:15]2[O:16][CH3:17])[n:6][cH:7]1.[ClH:49].[Na+:44].[O-:40][C:41]([OH:42])=[O:43]>>[Cl:1][c:2]1[cH:3][c:4]([NH:25][S:26](=[O:27])(=[O:28])[c:29]2[cH:30][c:31]([C:36]([F:37])([F:38])[F:39])[c:32]([Cl:35])[cH:33][cH:34]2)[c:5]([C:8](=[O:9])[c:10]2[c:11]([NH2:18])[cH:12][cH:13][cH:14][c:15]2[O:16][CH3:17])[n:6][cH:7]1

Participants

6

Reactant 5

HCID 176Acetic AcidHCID 313Hydrochloric AcidHCID 769Bicarbonate IonHCID 923Sodium ionHCID 66649350N-{2-[5-chloro-3-(4-chloro-3-trifluoromethyl-benzenesulfonylamino)-pyridine-2-carbonyl]-3-methoxy-phenyl}-2,2-dimethyl-propionamide

Product 1

HCID 57942469N-[2-(2-amino-6-methoxy-benzoyl)-5-chloro-pyridin-3-yl]-4-chloro-3-trifluoromethyl-benzenesulfonamide

Sources & evidence

ORD record
ord-5d0593dffb3d461eada2156ab133a579
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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