Imidazole → 2-[(tert-Butyldimethylsilyl)oxymethyl]-6-methoxybenzyl alcohol

HRID 827460Notes

Reaction equation

HRID 827460 reaction equation
[C:18]([CH3:19])([CH3:20])([CH3:21])[Si:22]([CH3:23])([CH3:24])[Cl:25].[CH3:1][O:2][c:3]1[c:4]([CH2:11][OH:12])[c:5]([CH2:9][OH:10])[cH:6][cH:7][cH:8]1.[O:27]1[CH2:28][CH2:29][CH2:30][CH2:31]1.[OH2:26].[nH:13]1[cH:14][cH:15][n:16][cH:17]1>>[CH3:1][O:2][c:3]1[c:4]([CH2:11][OH:12])[c:5]([CH2:9][O:10][Si:22]([C:18]([CH3:19])([CH3:20])[CH3:21])([CH3:23])[CH3:24])[cH:6][cH:7][cH:8]1

Participants

6

Reactant 5

HCID 795ImidazoleHCID 962WaterHCID 8028TetrahydrofuranHCID 28928tert-Butyldimethylsilyl chlorideHCID 14892485(3-Methoxy-1,2-phenylene)dimethanol

Product 1

HCID 468330582-[(tert-Butyldimethylsilyl)oxymethyl]-6-methoxybenzyl alcohol

Sources & evidence

ORD record
ord-603f0950358b470c9a5d952e01448cf4
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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