Borane → 6-bromo-8-fluoro-5-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine

HRID 827791Notes

Reaction equation

HRID 827791 reaction equation
[BH3:15].[Br:1][c:2]1[c:3]([CH3:14])[c:4]2[c:5]([c:11]([F:13])[cH:12]1)[O:6][CH2:7][C:8](=[O:10])[NH:9]2.[O:16]1[CH2:17][CH2:18][CH2:19][CH2:20]1>>[Br:1][c:2]1[c:3]([CH3:14])[c:4]2[c:5]([c:11]([F:13])[cH:12]1)[O:6][CH2:7][CH2:8][NH:9]2

Participants

4

Reactant 3

HCID 6331BoraneHCID 8028TetrahydrofuranHCID 712091776-bromo-8-fluoro-5-methyl-2H-benzo[b][1,4]oxazin-3(4H)-one

Product 1

HCID 712092976-bromo-8-fluoro-5-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine

Sources & evidence

ORD record
ord-0975b6af93dc4a6ba620cc865d2c859a
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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