Hydrochloric Acid → (4-Iodophenyl)-[4-(pyrrolidin-2-ylmethoxy)phenyl]methanone

HRID 827874Notes

Reaction equation

HRID 827874 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH:9]([CH2:13][O:14][c:15]2[cH:16][cH:17][c:18]([C:21]([c:22]3[cH:23][cH:24][c:25]([I:28])[cH:26][cH:27]3)=[O:29])[cH:19][cH:20]2)[CH2:10][CH2:11][CH2:12]1)([CH3:5])([CH3:6])[CH3:7].[ClH:30].[O:31]1[CH2:32][CH2:33][O:34][CH2:35][CH2:36]1>>[NH:8]1[CH:9]([CH2:13][O:14][c:15]2[cH:16][cH:17][c:18]([C:21]([c:22]3[cH:23][cH:24][c:25]([I:28])[cH:26][cH:27]3)=[O:29])[cH:19][cH:20]2)[CH2:10][CH2:11][CH2:12]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 69001039Tert-butyl 2-[[4-(4-iodobenzoyl)phenoxy]methyl]pyrrolidine-1-carboxylate

Product 1

HCID 59753020(4-Iodophenyl)-[4-(pyrrolidin-2-ylmethoxy)phenyl]methanone

Sources & evidence

ORD record
ord-dcd499744936478f97f9f0417ad5af1b
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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