Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 828588Generated: October 30, 2026

8-Amino-5,5-dimethyl-1,3,4,5-tetrahydro-benzo[b]azepin-2-one → {2-[5-Chloro-2-(5,5-dimethyl-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-8-ylamino)-pyrimidin-4-ylamino]-3-fluoro-phenoxy]-acetonitrile

https://huagongshe.com/reaction/828588

Reaction equation

Participants

RoleNameHCIDCharge
Reactant8-Amino-5,5-dimethyl-1,3,4,5-tetrahydro-benzo[b]azepin-2-oneHCID 57416062—
Reactant[2-(2,5-Dichloropyrimidin-4-ylamino)-3-fluorophenoxy]-acetonitrileHCID 86633948—
Product{2-[5-Chloro-2-(5,5-dimethyl-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-8-ylamino)-pyrimidin-4-ylamino]-3-fluoro-phenoxy]-acetonitrileHCID 66830311—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-c69b00002bfb449d8c074b745afb1d0b
Source noteTest data from https://doi.org/10.1039/C8SC04228D