Sulfuric Acid → 5-([1,1'-Biphenyl]-4-ylmethyl)pyrrolidin-2-one

HRID 828623Notes

Reaction equation

HRID 828623 reaction equation
[O:26]1[CH2:27][CH2:28][CH2:29][CH2:30]1.[S:21](=[O:22])(=[O:23])([OH:24])[OH:25].[c:1]1(-[c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[cH:2][cH:3][c:4]([C:7](=[O:8])[CH:9]2[CH2:10][CH2:11][C:12](=[O:14])[NH:13]2)[cH:5][cH:6]1>>[c:1]1(-[c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[cH:2][cH:3][c:4]([CH2:7][CH:9]2[CH2:10][CH2:11][C:12](=[O:14])[NH:13]2)[cH:5][cH:6]1

Participants

4

Reactant 3

HCID 1118Sulfuric AcidHCID 8028TetrahydrofuranHCID 17772957(r/s)-5-(Biphenyl-4-carbonyl)pyrrolidin-2-one

Product 1

HCID 593184595-([1,1'-Biphenyl]-4-ylmethyl)pyrrolidin-2-one

Sources & evidence

ORD record
ord-ec18eb11cd5d4a3e8cef17966fc68144
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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