反应详情

tert-Butyl 1-benzyl-7-(ethylsulfonamidomethyl)-1,2,3,4-tetrahydronaphthalen-2-ylcarbamate (0.652 g, 1.422 mmol) was dissolved in dichloromethane (5 mL) and trifluoroacetic acid (0.5 mL, 6.49 mmol) and stirred overnight at room temperature. The solution was evaporated and partitioned between saturated aqueous NaHCO3 and ethyl acetate. Water was extracted with ethyl acetate (2×30 mL). The collected organic extracts were dried on MgSO4 and evaporated under reduced pressure to give a brown oil.

1. customThe solution was evaporated
2. custompartitioned between saturated aqueous NaHCO3 and ethyl acetate
3. extractionWater was extracted with ethyl acetate (2×30 mL)
4. customThe collected organic extracts were dried on MgSO4
5. customevaporated under reduced pressure
6. customto give a brown oil