Toluene → N-[1-(4-Bromo-phenyl)-cyclopropanecarbonyl]-methanesulfonamide

HRID 828739Notes

Reaction equation

HRID 828739 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([C:11](=[O:12])[OH:13])[CH2:9][CH2:10]2)[cH:6][cH:7]1.[CH3:18][S:19](=[O:20])(=[O:21])[NH2:22].[CH3:23][CH2:24][N:25]([CH2:26][CH3:27])[CH2:28][CH3:29].[CH3:30][c:31]1[cH:32][cH:33][cH:34][cH:35][cH:36]1.[S:14]([Cl:15])([Cl:16])=[O:17]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([C:11](=[O:13])[NH:22][S:19]([CH3:18])(=[O:20])=[O:21])[CH2:9][CH2:10]2)[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 1140TolueneHCID 8471TriethylamineHCID 24386Thionyl ChlorideHCID 72879MethanesulfonamideHCID 162279661-(4-Bromophenyl)cyclopropane-1-carboxylic acid

Product 1

HCID 66577406N-[1-(4-Bromo-phenyl)-cyclopropanecarbonyl]-methanesulfonamide

Sources & evidence

ORD record
ord-3e5f1bd38a55485db362718a33126adf
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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