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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 828757Generated: October 30, 2026

Tetrahydrofuran → 2-(3,5-Difluorophenyl)-5-pentylpyrimidine

https://huagongshe.com/reaction/828757

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantNickel DichlorideHCID 24385—
Reactant1-Bromo-3,5-difluorobenzeneHCID 136313—
ReactantMagnesiumHCID 5462224—
Reactant2-Chloro-5-pentylpyrimidineHCID 16756526—
Product2-(3,5-Difluorophenyl)-5-pentylpyrimidineHCID 18348270—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-0b74fc697a5045fe8809de14d8d96d5e
Source noteTest data from https://doi.org/10.1039/C8SC04228D