Dichloromethane → 2,2-Dimethyl-3-(piperidine-4-yl)-propionic acid methyl ester
Reaction equation
[CH2:29]([Cl:30])[Cl:31].[CH3:1][O:2][C:3]([C:4]([CH2:5][CH:6]1[CH2:7][CH2:8][N:9]([C:12]([O:13][C:14]([CH3:15])([CH3:16])[CH3:17])=[O:18])[CH2:10][CH2:11]1)([CH3:19])[CH3:20])=[O:21].[OH:22][C:23]([C:24]([F:25])([F:26])[F:27])=[O:28]>>[CH3:1][O:2][C:3]([C:4]([CH2:5][CH:6]1[CH2:7][CH2:8][NH:9][CH2:10][CH2:11]1)([CH3:19])[CH3:20])=[O:21]Participants
4
Sources & evidence
- ORD record
- ord-212b40967a6e48ef84b01def57607051
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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