Hydrochloric Acid → 1-[2-[3-(3-Hydroxy-azetidin-1-yl)-phenyl]-5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]-2,2-dimethyl-propan-1-one
Reaction equation
[ClH:31].[I:1][c:2]1[cH:3][c:4](-[c:8]2[n:9][c:10]3[c:11]([n:12][cH:13]2)[n:14]([CH2:23][O:24][CH2:25][CH2:26][Si:27]([CH3:28])([CH3:29])[CH3:30])[cH:15][c:16]3[C:17]([C:18]([CH3:19])([CH3:20])[CH3:21])=[O:22])[cH:5][cH:6][cH:7]1.[NH:32]1[CH2:33][CH:34]([OH:36])[CH2:35]1>>[c:2]1([N:32]2[CH2:33][CH:34]([OH:36])[CH2:35]2)[cH:3][c:4](-[c:8]2[n:9][c:10]3[c:11]([n:12][cH:13]2)[n:14]([CH2:23][O:24][CH2:25][CH2:26][Si:27]([CH3:28])([CH3:29])[CH3:30])[cH:15][c:16]3[C:17]([C:18]([CH3:19])([CH3:20])[CH3:21])=[O:22])[cH:5][cH:6][cH:7]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-f68829d1d2f0446dabc96cb1d922e7a4
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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