Formaldehyde → N-(3-Fluoro-4-(2-(1-methylpiperidin-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-2-(4-fluorophenyl)-3-oxo-2,3-dihydropyridazine-4-carboxamide
Reaction equation
[CH2:41]=[O:42].[CH2:43]1[O:44][CH2:45][CH2:46][CH2:47]1.[F:1][c:2]1[cH:3][c:4]([NH:24][C:25](=[O:26])[c:27]2[c:28](=[O:40])[n:29](-[c:33]3[cH:34][cH:35][c:36]([F:39])[cH:37][cH:38]3)[n:30][cH:31][cH:32]2)[cH:5][cH:6][c:7]1[O:8][c:9]1[c:10]2[c:11]([n:12][cH:13][cH:14]1)[cH:15][c:16]([CH:18]1[CH2:19][CH2:20][NH:21][CH2:22][CH2:23]1)[s:17]2>>[F:1][c:2]1[cH:3][c:4]([NH:24][C:25](=[O:26])[c:27]2[c:28](=[O:40])[n:29](-[c:33]3[cH:34][cH:35][c:36]([F:39])[cH:37][cH:38]3)[n:30][cH:31][cH:32]2)[cH:5][cH:6][c:7]1[O:8][c:9]1[c:10]2[c:11]([n:12][cH:13][cH:14]1)[cH:15][c:16]([CH:18]1[CH2:19][CH2:20][N:21]([CH3:41])[CH2:22][CH2:23]1)[s:17]2Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-d39a1bd1e2a74aab8f09b3787c521f03
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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