Methanol → 3-(Aminomethyl)-5-bromopyridine

HRID 829035Notes

Reaction equation

HRID 829035 reaction equation
[Br:1][c:2]1[cH:3][c:4]([CH2:8][N:9]([C:10]([O:11][C:12]([CH3:13])([CH3:14])[CH3:15])=[O:16])[C:17]([O:18][C:19]([CH3:20])([CH3:21])[CH3:22])=[O:23])[cH:5][n:6][cH:7]1.[CH3:34][OH:35].[Cl:31][CH2:32][Cl:33].[OH:24][C:25]([C:26]([F:27])([F:28])[F:29])=[O:30]>>[Br:1][c:2]1[cH:3][c:4]([CH2:8][NH2:9])[cH:5][n:6][cH:7]1

Participants

5

Reactant 4

HCID 887MethanolHCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 22265925Di-tert-butyl(5-bromo-3-pyridinyl)methylimidodicarbonate

Product 1

HCID 229922643-(Aminomethyl)-5-bromopyridine

Sources & evidence

ORD record
ord-33e6cc1646e84baab5420a67f07b4c12
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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