Ammonium → 8-(4-Methylpiperazin-1-yl)naphthalen-2-ol

HRID 829072Notes

Reaction equation

HRID 829072 reaction equation
[C:13](=[O:14])([OH:15])[O-:16].[CH2:47]([Cl:48])[Cl:49].[CH3:21][N:22]([CH2:23][CH2:24][Cl:28])[CH2:26][CH2:27][Cl:25].[CH3:42][C:43]#[N:44].[CH3:45][OH:46].[ClH:20].[I-:19].[NH2:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[cH:7][cH:8][c:9]([OH:12])[cH:10][c:11]12.[NH4+:29].[Na+:17].[Na+:18].[OH-:30].[c:31]1([OH:32])[c:33]2[c:34]([cH:35][cH:36][cH:37][cH:38]2)[cH:39][cH:40][cH:41]1>>[N:1]1([c:2]2[cH:3][cH:4][cH:5][c:6]3[cH:7][cH:8][c:9]([OH:12])[cH:10][c:11]23)[CH2:24][CH2:23][N:22]([CH3:21])[CH2:26][CH2:27]1

Participants

13

Reactant 12

HCID 223AmmoniumHCID 313Hydrochloric AcidHCID 769Bicarbonate IonHCID 887MethanolHCID 923Sodium ion2×HCID 961HydroxideHCID 4033MechlorethamineHCID 6342AcetonitrileHCID 6344DichloromethaneHCID 70051-NaphtholHCID 83588-Amino-2-naphthalenolHCID 30165Iodide Ion

Product 1

HCID 108002178-(4-Methylpiperazin-1-yl)naphthalen-2-ol

Sources & evidence

ORD record
ord-4eedd86e8df34dafbac732c3be13ef73
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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