Dimethylformamide → 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 34

HRID 829655Notes

Reaction equation

HRID 829655 reaction equation
[CH3:31][N:32]([CH3:33])[CH:34]=[O:35].[Cl:1][c:2]1[c:3](-[c:9]2[cH:10][c:11]3[c:12]([n:13][c:14]([S:17][CH3:18])[n:15][cH:16]3)[n:19]([CH3:22])[c:20]2=[O:21])[c:4]([Cl:8])[cH:5][cH:6][cH:7]1.[NH2:23][CH2:24][c:25]1[n:26][cH:27][cH:28][cH:29][cH:30]1>>[Cl:1][c:2]1[c:3](-[c:9]2[cH:10][c:11]3[c:12]([n:13][c:14]([NH:23][CH2:24][c:25]4[n:26][cH:27][cH:28][cH:29][cH:30]4)[n:15][cH:16]3)[n:19]([CH3:22])[c:20]2=[O:21])[c:4]([Cl:8])[cH:5][cH:6][cH:7]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 195092-PyridinemethanamineHCID 107367016-(2,6-Dichlorophenyl)-8-methyl-2-(methylthio)pyrido[2,3-d]pyrimidin-7(8H)-one

Product 1

HCID 53278812-aminopyrido[2,3-d]pyrimidin-7(8H)-one 34

Sources & evidence

ORD record
ord-07250f95235c4af1aa4a635061a439c2
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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