Dichloromethane → (+/-)-1-(3-Bromo-5-chloro-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-indazol-7-yl)ethyl 2,2,2-trichloroacetimidate

HRID 829749Notes

Reaction equation

HRID 829749 reaction equation
[Br:1][c:2]1[n:3][n:4]([CH2:15][O:16][CH2:17][CH2:18][Si:19]([CH3:20])([CH3:21])[CH3:22])[c:5]2[c:6]([CH:12]([CH3:13])[OH:14])[cH:7][c:8]([Cl:11])[cH:9][c:10]12.[CH2:40]([Cl:41])[Cl:42].[Cl:34][C:35]([C:36]#[N:37])([Cl:38])[Cl:39].[N:23]12[CH2:24][CH2:25][CH2:26][N:27]=[C:28]1[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33]2>>[Br:1][c:2]1[n:3][n:4]([CH2:15][O:16][CH2:17][CH2:18][Si:19]([CH3:20])([CH3:21])[CH3:22])[c:5]2[c:6]([CH:12]([CH3:13])[O:14][C:36]([C:35]([Cl:34])([Cl:38])[Cl:39])=[NH:37])[cH:7][c:8]([Cl:11])[cH:9][c:10]12

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 11011TrichloroacetonitrileHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 57546143HCID 57546143, compound

Product 1

HCID 57546223(+/-)-1-(3-Bromo-5-chloro-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-indazol-7-yl)ethyl 2,2,2-trichloroacetimidate

Sources & evidence

ORD record
ord-2a91b9c0ad43458299f5f9f957d07746
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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