Hydrochloric Acid → 3-(4-fluoro-2,3-dihydro-1H-indol-5-yl)furo[3,2-c]pyridin-4-amine

HRID 830133Notes

Reaction equation

HRID 830133 reaction equation
[ClH:28].[NH2:1][c:2]1[n:3][cH:4][cH:5][c:6]2[c:7]1[c:8](-[c:11]1[c:12]([F:27])[c:13]3[c:17]([cH:18][cH:19]1)[N:16]([C:20]([O:21][C:22]([CH3:23])([CH3:24])[CH3:25])=[O:26])[CH2:15][CH2:14]3)[cH:9][o:10]2.[O:29]1[CH2:30][CH2:31][O:32][CH2:33][CH2:34]1>>[NH2:1][c:2]1[n:3][cH:4][cH:5][c:6]2[c:7]1[c:8](-[c:11]1[c:12]([F:27])[c:13]3[c:17]([cH:18][cH:19]1)[NH:16][CH2:15][CH2:14]3)[cH:9][o:10]2

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 668239041,1-dimethylethyl 5-(4-aminofuro[3,2-c]pyridin-3-yl)-4-fluoro-2,3-dihydro-1H-indole-1-carboxylate

Product 1

HCID 668240273-(4-fluoro-2,3-dihydro-1H-indol-5-yl)furo[3,2-c]pyridin-4-amine

Sources & evidence

ORD record
ord-934bd98923da42b4aea69f8dfabdb853
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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