Dichloromethane → 7-Morpholin-4-yl-4-(3-[1,2,4]triazol-4-yl-phenyl)-8-trifluoromethyl-1,3-dihydro-benzo[b][1,4]diazepin-2-one
Reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][c:8]1[c:9]([NH:24][C:25]([CH2:26][C:27](=[O:5])[c:28]2[cH:29][c:30](-[n:34]3[cH:35][n:36][n:37][cH:38]3)[cH:31][cH:32][cH:33]2)=[O:40])[cH:10][c:11]([C:20]([F:21])([F:22])[F:23])[c:12]([N:14]2[CH2:15][CH2:16][O:17][CH2:18][CH2:19]2)[cH:13]1)([CH3:6])([CH3:39])[CH3:41].[Cl:49][CH2:50][Cl:51].[F:42][C:43]([F:44])([F:45])[C:46]([OH:47])=[O:48]>>[N:7]1=[C:27]([c:28]2[cH:29][c:30](-[n:34]3[cH:35][n:36][n:37][cH:38]3)[cH:31][cH:32][cH:33]2)[CH2:26][C:25](=[O:40])[NH:24][c:9]2[c:8]1[cH:13][c:12]([N:14]1[CH2:15][CH2:16][O:17][CH2:18][CH2:19]1)[c:11]([C:20]([F:21])([F:22])[F:23])[cH:10]2Participants
4
Sources & evidence
- ORD record
- ord-d1876dd27adf49898d034c1e2108aa42
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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